app.ivive/ivive · v1.0.1 · other
ivive.app is healthy: it completed an MCP handshake in 1277 ms and exposes 6 tools.
Human hepatic clearance from in-vitro CLint, with the error band measured on known drugs.
Endpoint: https://api.ivive.app/mcp/ (streamable-http)
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| Users (last 30 days) | 0 |
| Handshake | Healthy |
| Auth needed | None |
| Tool count | 6 |
| Latency | 1277 ms |
| Last checked (UTC) | 2026-10-17T09:10:32.468Z |
| Checked (UTC) | Status | Latency | Error |
|---|---|---|---|
| 2026-10-17T09:10:32.468Z | Healthy | 1277 |
predict_inputs | Predict fu,p and fu,inc from a SMILES, with structure-only human CL and Vss as second opinions. Predictions, not measurements; check the applicability verdict. |
calc_clhep | Hepatic and plasma clearance from in-vitro CLint, fu,mic and fu,p (IVIVE), with the observed-CL band and applicability warnings. If fu,p or fu,mic came from predict_inputs, tell the user the result rests on predicted inputs. |
target_clint | The in-vitro CLint an assay must read for a compound to reach a target plasma clearance. |
input_sensitivity | How far plasma CL moves as each input is varied over a range, e.g. a predicted fu,p over its 50% range. |
similar_drugs | Most similar reference drugs to a SMILES, with observed and IVIVE-predicted clearance: how IVIVE fared on this kind of structure. |
scale_to_human | Predict human plasma CL from observed animal in-vivo CL (rat, dog, monkey), every applicable method with its measured error. Observed animal CL only, never predicted. |