io.github.cyanheads/chembl-mcp-server · v0.3.3 · health-and-science
io.github.cyanheads/chembl-mcp-server is healthy: it completed an MCP handshake in 3421 ms and exposes 7 tools.
Link compounds to protein targets, rank bioactivity, and look up drug mechanisms and indications.
Endpoint: https://chembl.caseyjhand.com/mcp (streamable-http)
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| Users (last 30 days) | 0 |
| Handshake | Healthy |
| Auth needed | None |
| Tool count | 7 |
| Latency | 3421 ms |
| Last checked (UTC) | 2026-10-15T03:20:52.267Z |
| Checked (UTC) | Status | Latency | Error |
|---|---|---|---|
| 2026-10-15T03:20:52.267Z | Healthy | 3421 |
chembl_search_molecules | Discovery entry point for compounds. Find by name / ChEMBL ID / InChIKey with the default search_type=name (supply query), or run a structure search with search_type exact | similarity | substructure (supply structure as a SMILES). At least one of query or structure is required, and structure is req |
chembl_get_bioactivities | The flagship compound↔target bioactivity bridge: measurements for a molecule (target deconvolution / selectivity), a target (lead finding), or both together (how potently one compound hits one target). Supply at least one of molecule_chembl_id (from chembl_search_molecules) or target_chembl_id (from |
chembl_search_targets | Resolve a protein/gene/UniProt accession to the ChEMBL target ID that chembl_get_bioactivities needs for the target→leads workflow. Supply at least one of accession (UniProt, e.g. P00533), gene_symbol (e.g. EGFR), or query (free-text name); filter further by organism and target_type. Returns each ta |
chembl_get_drug_info | Pharmacology for a drug (molecule): mechanism(s) of action, the molecular target(s) it acts on, action type (inhibitor / agonist / …), first-approval year, and clinical indications with the max phase reached for each. Supply molecule_chembl_id (from chembl_search_molecules). Distinct from the openfd |
chembl_get_assay | Assay provenance behind a bioactivity row: description, type (binding / functional / ADMET / toxicity), the target it measures, organism, and ChEMBL's 1–9 confidence score (9 = direct assay on the protein target, lower = homologous or indirect). Supply assay_chembl_id from a chembl_get_bioactivities |
chembl_dataframe_query | Run a read-only SQL SELECT over the bioactivity rows chembl_get_bioactivities spilled to a canvas — rank, group, dedupe, and aggregate across the FULL set, not the inline preview. Reference each staged table by the name chembl_get_bioactivities returned — bioactivities for its potency_ranked view, b |
chembl_dataframe_describe | List the tables and columns staged on a canvas by chembl_get_bioactivities — inspect before calling chembl_dataframe_query to write correct SQL. Returns each table with its row count, kind (table | view), and column names + types. Requires CANVAS_PROVIDER_TYPE=duckdb. |